What is the main symptom associated with urticaria?

The main symptom associated with urticaria, commonly known as hives, is indeed a rash. This rash typically presents as raised, itchy welts on the skin that can vary in size and shape. Urticaria occurs as a result of the body's release of histamine and other chemicals, leading to inflammation and the characteristic appearance of the rash. The hives may appear suddenly and can be triggered by various factors, including allergens, medications, or physical stimuli.

While nausea, fatigue, and headache can accompany other medical conditions or be secondary symptoms in various scenarios, they are not the defining characteristics of urticaria. The immediate and distinguishing feature of this condition is the rash, which is a direct result of the body's immune response.